CURES Funded Pilot Projects
PIs | Project Title |
Joseph Caruso, Shawn McElmurry | Petcoke in an urban environment |
Fei Chen, Jeffrey Howard | Detroit Soil Arsenic and Its Association with Carcinogenesis |
Malcolm Cutchin, Cathy Lysack,Rich Slatcher | Daily Activities, Neighborhood Stressors, and Stress of Older African-Americans |
Carmen Giurgescu, Paul Stemmer,et al. | Chronic Stressors, Proteome Profiles and Preterm Birth in African American Women |
Paul Stemmer, Allen Rosenspire | Novel Exposure Signatures for Mercury Intoxication of the Immune System |
Bengt Arnetz | The Interaction between Pb and Trauma on the Epigenome and Proteome in Refugees |
Moriah Thomason, Douglas Ruden | Maternal Lead Exposure Alters Offspring Brain and Epigenetics Two Decades Later |
Yifan Zhang, Lawrence Lemke,Weilong Hao, Shawn McElmurry, Patrick Crouch | Heavy Metals and the Development of Antibiotic Resistance in Urban Agriculture |
Samson Jamesdaniel | Synergism between noise and lead in inducing hearing loss |
Todd Leff, Colleen Buggs-Saxton | Does Pediatric Exposure to Lead (Pb) Increase the Risk of Diabetes? |
Douglas Ruden,Mona Hanna-Attisha | Spatial and Temporal Analyses of Neonatal Blood Lead Levels of Flint Children |
Tracie Baker, David Pitts,Shawn McElmurry | The use of novel assay systems to evaluate cardiac, reproductive, and neurobehavioral effects of volatile organic chemicals (VOCs) in aquatic model organisms |
Alana Conti | Comorbidity of PTSD and Alcohol Dependence: Endocannabinoid Regulation |
Wanqing Liu, Andrea Cassidy-Bushrow | Heavy Metals and Nonalcoholic Fatty Liver Disease |
Moh Malek | Impact of Prenatal Arsenic Exposure on Offspring Skeletal Muscle Metabolism |
Paul Stemmer, Judy Westrick | Microcystin Toxicity is Increased by Underlying Liver Disease and Obesity |
Moriah Thomason, Christopher Trentacosta | Prenatal temporal dynamics in heavy metal exposure & longitudinal fetal and child neurodevelopment |
Tracie Baker, Yongli Zhang | The Occurrence of Microplastics in Drinking Water and the Consequential Impact on Human Health |
James Granneman, Elizabeth Rondini | Impact of obesogens on developmental programming of white adipose tissue in mice |
Linda Hazlett | Airborne Particulates, Ocular Surface Stress and Infection |
Kezhong Zhang, Lawrence Grossman | Air Pollution-induced Diabetes: Dysregulation of Energy Homeostasis by Disruption of Mitochondria and ER Associated Membrane |
Jennifer Straughen, Andrea Cassidy-Bushrow | Intrauterine origins of autism spectrum disorder: impact of exposure to metals |
Tracie Baker, Shawn McElmurry, Nancy Love | Impact of changes in drinking water quality on gut microbiome |
Rodrigo Fernandez-Valdivia, Carol Miller, Mala Hettiarachchi | Decoding PFAS Exposure in Cancer Initiation and Progression |
Douglas Ruden, Daniel Rappolee | Effects of Phthalates on Epigenetic Reprogramming of Embryonic Stem Cells (ESCs) |
Marianna Sadagurski, Ulrike Klueh | Benzene exposure promotes neuroinflammation and metabolic dysregulation |
Jennifer Straughen, Yalei Chen | Bridging exposure to BTEX and preterm birth in African Americans: the role of DNA methylation |
Christopher Kassotis | Enhanced Metabolic Disruption from Co-Exposures to Organic and Inorganic Pollutants |
Izabela Podgorski | Effects of PFAS exposure on bone microenvironment: implications for bone-metastatic prostate cancer |
Carol Miller | Exploring Mechanisms and Pathways of VOC Migration Beneath Detroit's Neighborhoods: Implications for Vapor |
Wanqing Liu and Michael Petriello | PFAS and Liver Injuries at Different Developmental Stages: A Genomic Approach |
Jen Straughen and Andrea Cassidy-Bushrow | Maternal inflammation and environmental toxicants: investigating the associations and needs of Detroit women |
Hilary Marusak | Effects of urban air pollution on neurodevelopmental markers of anxiety risk during adolescence |
Paul Stemmer and Heather Gibson | Individual Determinants of Mercury-Induced Disease Identified Using the Diversity Outbred Mouse Model |
Jiahui Ding | Impact of maternal benzene exposure on fetal lung immune adaptation |
Michael Petriello and Richard Pilsner | PFAS mixtures disrupt sperm methylation and increase cardiometabolic disease risk in offspring |
Christopher Kassotis | Cardiometabolic health consequences of artificial turf-associated contaminants |
Francesca Luca | Single cell genomic analysis of PFAS and inflammation among older African American adults |